In a new study that was published in Scientific Reports, a team of researchers from the National Centre for Biological Sciences (NCBS) studied the functioning of special circular proteins in plants called “cyclotides”, which the pharma industry uses ...

Calcium is as vital to neurons as musical notes are for a song. Levels of calcium oscillate like crescendos, regulating neuronal communication, function and survival. Also, much like cringing to wrong notes, calcium imbalance is seldom tolerated by neurons. In fact, derailed cellular calcium levels are a harbinger of certain neurodegenerative disorders in humans. Hence to regulate calcium traffic, neurons harbor vigilant protein passages and compartments.

It is with deep sadness that we acknowledge the passing of Shri R.D. John on the morning of 26 July 2020.

COVID-19 response by scientists at DBT-inStem and NCBS-TIFR, Bengaluru

Proteins often use Ubiquitin tags to be shuttled within cells or dispatched for degradation. Although small in demeanor, Ubiquitins are hugely influential.

The National Centre for Biological Sciences is delighted to welcome Shaon Chakrabarti, who joins the Centre as its newest faculty member.

Shaon’s research combines theory and experiments to study cellular proliferation at the single cell level -- its underlying physical principles, control mechanisms, and consequences in development and disease. The eventual goal of his research is to build on these basic principles to improve therapeutic strategies in the clinical treatment of cancer.

The BLiSC community congratulates Prof. Sumantra Chattarji on his election as a lifetime member of the EMBO in recognition of his remarkable achievements in the life sciences.

Along with the those on the frontlines, thousands of researchers around the world are working to identify the right approach to tackling the COVID-19 pandemic from various angles and disciplines. The search for effective treatment options and vaccinations for the SARS-CoV-2 has occupied scientists and medical researchers in recent months in an unprecedented manner.

Researchers at the Bengaluru-based National Centre for Biological Sciences (NCBS) have identified 33 small molecules out of 3, 30,000 that can target one protein — NSP1 — in the Sars-Cov-2 virus, which causes Covid-19. Identifying these molecules may help with drug discovery and examining existing drugs, approved by the Food and Drug Administration (FDA), that can be repurposed to treat Covid-19.