Researchers at the Bengaluru-based National Centre for Biological Sciences have come up with a finding that could pave the way for developing a new treatment for type 2 diabetes.

The scientists have found that an enzyme called PIP4K in the body plays a major role in determining the ability of cells to detect and respond to the hormone insulin. The reduced ability of cells to respond to insulin following a meal results in Type 2 diabetes. The condition is an important health problem.

Image: Despite more than a million fold difference in the light intensity, our brains enable us to see the same scene in broad daylight and a dim night by the process of normalization. This article shows how brains "can" perform normalization by precisely balancing two equal and opposite forces - excitation and inhibition.

Artist of the graphic: Hrishikesh Nambisan

The newly described snake belongs to the family Colubridae—the largest family of snakes with more than 1,700 species. The family name comes from the Latin word for snake—coluber. S. atemporalis falls under Natricinae, a subfamily of colubrid snakes that are found in or near water, and have rotund bodies and heads that are broader than their bodies.

A newly discovered species of gecko, a nocturnal and often highly vocal lizard usually found in warm regions, which was discovered in Tamil Nadu by NCBS researchers, has been named after Tejas Thackeray.

Researchers have finally unravelled how each part of drumstick (Moringa oleifera), the “magic tree”, is nutritionally rich compared with other plants such as rice, papaya, spinach and cocoa. All the five tissues — stem, root, leaf, flower and seed — of drumstick studied were found to be rich either in certain vitamins or essential minerals.

A team led by Prof. Ramanathan Sowdhamini from the National Centre for Biological Sciences (NCBS), Bengaluru analysed the genes on complimentary DNA (cDNA) of all the five tissues.

Researchers at the National Centre for Biological Sciences (NCBS) uncovered an elaborate biochemical factory inside the Moringa plant, leading to the production of five drug-like molecules and three vitamins (vitamin A, C, E).
 

A mutant fruitfly strain studied by researchers from the National Centre for Biological Sciences (NCBS), Bangalore, may hold the key to understanding what goes wrong with insulin signalling in type-2 diabetes. When raised on a high-sugar diet, normal flies show a 25% increase in blood sugar levels; but the mutant flies—which lack the enzyme PIP4K (short for phosphatidylinositol 5 phosphate 4-kinase)— have normal blood sugar levels when raised on a high-sugar diet.

Recently, six scientists, Abi Tamim Vanak, Ankila Hiremath and Nitin Rai of the Ashoka Trust for Research in Ecology and the Environment; Raman Sukumar of the Centre for Ecological Sciences at the Indian Institute of Science; Jayashree Ratnam of the National Centre for Biological Sciences; and Tarsh Thekaekara of

Did you ever wonder why our grandmothers insisted on having a Tulsi plant (Holy Basil) in front of the house and a Moringa (Drumstick) tree in the backyard? Each and every part of the drumstick tree has a medicinal value and is a rich source of nutrients and minerals.