NCBS Research

The research scene at NCBS
Friday, February 3rd, 2012

Shinya Yamanaka, the doyen of stem cell biology, was at NCBS on 30th January 2012. In Bangalore to deliver a talk at the Indian Institute of Science as part of the Cell Press-TNQ India Distinguised Lectureship series, he took time out from his hectic schedule to interact with students from NCBS and inStem.

Monday, January 30th, 2012

The Howard Hughes Medical Institute (HHMI) have announced their first International Early Career Scientist Awards and Sandhya P. Koushika is one of the 28 recipients. She is the only awardee based in India.

Wednesday, January 18th, 2012

NCBS alumni Ganesan Pugalenthi is getting plaudits for his work on bioinformatics algorithms, softwares and tools. He won the 2011 Bioclues Innovation, Research and Development (BIRD) Award, which is given every year for outstanding contributions in the field of functional genomics and bioinformatics by Bioclues, a non-profit virtual organisation "for, by and of" Indian bioinformaticians. The award ceremony was held on 23rd December 2011 at the National Institute of Nutrition, Hyderabad.

Friday, January 6th, 2012

NCBS installed a symmetric multiprocessing (SMP) cluster, the largest of its kind in India, on 28th December 2011. SMP clusters are used for high-performance computing, where calculations are carried out in parallel. The system at NCBS is a Silicon Graphics Inc. (SGI) Ultra Violet (UV) 1000 SMP cluster.

Thursday, December 1st, 2011

NCBS's alumnus Santosh Kumar Jha has won the TAA-Zita Lobo Memorial Award 2010-2011 for his Ph.D. thesis. His doctoral work titled Characterization of the nature of free energy barriers during the folding and unfolding of small proteins looked at noncooperative and polymer natures of protein folding and unfolding reactions. His work also provided the first direct experimental evidence in support of the 20-year old dry molten globule hypothesis in the field. Jayant Udgaonkar was Jha's Ph.D. Supervisor.

Monday, August 1st, 2011

Malaria may be severely affecting conservation efforts in Pakke Tiger Reserve, according to a recent study by authors Nandini Velho, Umesh Srinivasan, N.S. Prashanth and William F. Laurance, published in the current issue of Biological Conservation.

Saturday, June 25th, 2011
As in many parts of the world, soil salinity is a chronic condition in cultivable lands across most of India. Water provided by irrigation is saltier than rain, and so increased dependence on irrigation, and inadequate drainage systems, are causing soil salt to build up to toxic levels. Plant scientists are trying to develop crop varieties and management strategies that lead to higher salt tolerance. Pannaga Krishnamurthy and M.K. Matthew, from NCBS and their international colleagues* recently developed an elegant and practical technique to induce salt tolerance in rice, reported in the Journal of Experimental Botany.
Friday, June 3rd, 2011

Sandeep Krishna recently joined the NCBS faculty. As playful and fun to talk to as he professes to be below, he agreed without hesitation to take part in a hypothetical discussion. This is the set-up: Sandeep has just boarded a train to Chennai and, taking his seat, he finds himself next to the sharp-minded matriarch of the Bhatia dynasty, Mrs Lakshmi Bhatia. She has a vast reservoir of disposable cash and is eagerly looking for worthwhile projects to finance. Let's eavesdrop on their conversation as they watch the dry and dusty southern Indian landscape roll by...

So Sandeep, please tell me about this research that you do in Bangalore.

Sandeep: Sure. I do a lot of theoretical work. I'm interested in what one could call basic science, not that I think there is a sharp line between basic and applied research. We are trying to understand phenomena at many different scales, the way that organisms function, how they are built, why they are built that way, how they manage to interact with the environment. More specifically, I focus on cells and information: how do cells get information about their environment, how do they deal with, and make decisions based on, all this information? We know that there are regulatory networks that determine these decisions, I want to understand the principles that govern the operation and evolution of those networks.

Tuesday, May 24th, 2011

Vatsala Thirumalai, a recent addition to the NCBS faculty line-up, can barely remember a time when she wasn't fascinated by neuroscience. In the interview below she tells how she is particularly interested in how the growth of the nervous system is coupled to the overall growth of an animal. A humble person, Vatsala explains her own growth as a developmental biologist largely in terms of the wonderful mentors she has had throughout her career.

G: How did you get into science?

V: I really was interested in neuroscience from the very beginning, that's what brought me into science. The interest in neuroscience came from two or three different avenues. One was that I liked biology a lot but if you looked in high school biology textbooks, then in physiology there are lessons on how respiration works, how circulation works, how the kidney works, and all that, but when you go to the nervous system, there was nothing really given in the textbooks. They only covered that simple monosynaptic reflex arc - you hit your kneecap and your leg flies up. And then they describe the different regions of the brain, cerebrum, cerebellum, spinal cord and so on. But that was about it.  They never told you what was really going on in these brain regions, in the type of detail you would find for, say, the circulatory system. You know: all the chambers of the heart and how the flow goes from one to the next, through the lung, the oxygenation. When I asked my teacher Ms. Getsie about it, she told me that that was because we didn't know much about how the brain works. That piqued my interest in neuroscience. And on top of that philosophically I was interested in the nature of thoughts, why do we have thoughts, and what are they made of, is there a soul etc etc.,  so I really wanted to follow neurobiology and be a scientist.

Tuesday, February 15th, 2011

Namrata Jayanth, a PhD student in Mrinalini Puranik's lab at NCBS was recently awarded a highly competitive travel award to attend the 2011 annual meeting of the American Society for Biochemistry and Molecular Biology in Washington. Below, Namrata talks about the conference and her research.

Namrata, is this your first big international conference?

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